Zonisamide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- nausea.
- vomiting.
- weight loss.
- changes in taste.
- diarrhea.
- constipation.
- heartburn.
- dry mouth.
What are the long term side effects of zonisamide?
Table 2
| Adverse effect | Leppik20* | Leppik et al19*,& |
|---|---|---|
| Anorexia or decreased appetite | 201 (16.7%) | 17 (15%) |
| Fatigue or tiredness or asthenia | 182 (15.1%) | 10 (8.8%) |
| Nausea | 159 (13.2%) | 17 (15%) |
| Headache | 145 (12%) | 18 (15.9%) |
Do zonisamide side effects go away?
Some side effects of zonisamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
How does zonisamide make you feel?
This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away.
What drugs should not be taken with zonisamide?
Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana (cannabis), antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and opioid pain relievers (such as codeine).
Does zonisamide help with anxiety?
Results from this pilot and open naturalistic study suggest that zonisamide may effectively augment response to anxiolytic medications in patients with treatment refractory anxiety. Larger and controlled studies are warranted to confirm these preliminary findings.
Can zonisamide cause weight gain?
Longitudinal assessment indicated that zonisamide was associated with a significantly slower rate of BMI and weight increases compared with placebo (P = . 01). No patients in the zonisamide group experienced significant weight gain, compared with 33% of placebo-treated patients (P = . 009).
Can zonisamide cause memory loss?
Zonisamide administered in a high, acute dose impairs the spatial memory. The drug given repeatedly disturbs spatial memory in the initial phase of the study. Zonisamide administered repeatedly impairs emotional memory.
Does zonisamide affect blood pressure?
Both zonisamide and CPAP led to a reduction of diastolic blood pressure (p=0.01 and 0.048, respectively) (table 4) but there were no between-group differences in changes of systolic blood pressure, diastolic blood pressure or heart rate.
Can zonisamide cause vision problems?
Taking zonisamide can cause permanent vision loss. Tell your doctor right away if you have any eye pain or redness or any changes in your vision. Some people have thoughts about suicide while taking zonisamide. Stay alert to changes in your mood or symptoms.
Is zonisamide used for anxiety?
Is zonisamide a mood stabilizer?
Zonegran (zonisamide) is used with other medicines to help control partial seizures. It can’t be used by itself. Prevents seizures and stabilizes mood.
What are the most common side effects of zonisamide?
Zonisamide Side Effects 1 More Common. 2 Less Common. Some side effects of zonisamide may occur that usually do not need medical attention. 3 General. The most common adverse reactions to this drug are somnolence, dizziness, and anorexia. 4 Gastrointestinal. 5 Nervous system. 6 (more items)
How many milligrams of Baulac can you take for seizures?
Focal (partial) onset seizures: Note: FDA approved for adjunctive treatment of focal onset seizures; may be used off label as monotherapy for focal onset seizures (Baulac 2012; Baulac 2014): Oral: Initial: 100 mg/day. Dose may be increased to 200 mg/day after 2 weeks.
How many milligrams of zonisamide do you give a baby?
Suzuki treated 11 newly diagnosed infants (mean age: ~6 months) with zonisamide monotherapy starting at doses of 3 to 5 mg/kg/day given in 2 divided doses/day; doses were increased every 4th day until seizures were controlled or a maximum dose of 10 mg/kg/day was attained; four of 11 patients responded at doses of 4 to 5 mg/kg/day (Suzuki 1997).
Is zonisamide an anticonvulsant for dogs?
Zonisamide is used as an anticonvulsant in dogs and cats. h Based on the authorÕs clinical experience, zonisamide may be e!ective when used as monotherapy or in conjunction with other anticonvulsants (eg, phenobarbital, potassium bromide, levetiracetam).
