The Dengue Serotypes Dengue infections are caused by four closely related viruses named DEN-1, DEN-2, DEN-3, and DEN-4. These four viruses are called serotypes because each has different interactions with the antibodies in human blood serum.
How many serotypes of the dengue virus has?
Key facts. Dengue is a mosquito-borne viral infection, found in tropical and sub-tropical climates worldwide, mostly in urban and semi-urban areas. The virus responsible for causing dengue, is called dengue virus (DENV). There are four DENV serotypes, meaning that it is possible to be infected four times.
What is the difference between dengue serotypes?
Previous reports of dengue in children have suggested that infection with secondary DENV-2 is more likely to result in severe disease compared with other serotypes. In contrast, primary DENV-1 cases were more overt whereas primary DENV-2 and DENV-3 cases were usually silent.
How are dengue virus classified?
Dengue is classified as (1) undifferentiated fever, (2) dengue fever (DF), and (3) dengue hemorrhagic fever (DHF). In addition to fever and at least 2 clinical findings, diagnosis of DF requires epidemiological or laboratory evidence supporting a dengue virus infection.
What is serotypes in virus?
A serotype or serovar is a distinct variation within a species of bacteria or virus or among immune cells of different individuals. These microorganisms, viruses, or cells are classified together based on their surface antigens, allowing the epidemiologic classification of organisms to the subspecies level.
What is serotype 2 dengue?
Dengue serotype 2 (DEN-2) viruses with the potential to cause dengue hemorrhagic fever have been shown to belong to the Southeast (SE) Asian genotype. These viruses appear to be rapidly displacing the American genotype of DEN-2 in the Western Hemisphere.
What does serotype mean?
Serotypes are groups within a single species of microorganisms, such as bacteria or viruses, which share distinctive surface structures.
Is dengue virus single or double stranded?
Dengue virus (DENV) belongs to the family Flaviviridae, genus Flavivirus. It is a single-stranded positive-sense ribonucleic acid virus with 10,700 bases.
WHO dengue 2009 classification?
Dengue classification according to the World Health Organization guidelines issued in 2009. Dengue is classified as dengue with or without warning signs and severe dengue. Diagnosis of dengue requires the presence of fever and at least 2 clinical findings or any warning signs.
What is serotype and genotype?
As nouns the difference between serotype and genotype is that serotype is a group of microorganisms characterised by a specific set of antigens while genotype is genotype.
What is biotype and serotype?
We learned that a serotype is a serologically and antigenically distinct variety of microorganism, like a subgroup of a species of bacteria. And, finally, we learned that a biotype is a strain, distinguished from other microorganisms of the same species, by its physiological properties.
Which dengue serotype is most common?
Dengue virus infection is estimated to cause infection in approximately 390 million people globally each year, of which 96 million develop clinical disease. Dengue serotype 2 (DEN-2) is the most prevalent serotype over the past 50 years in India, but serotypes 3 and 4 have appeared in some epidemics as well.
