Cyclophosphamide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- nausea.
- vomiting.
- loss of appetite or weight.
- abdominal pain.
- diarrhea.
- hair loss.
- sores on the mouth or tongue.
- changes in skin color.
What is the most common side effect of cyclophosphamide?
Cyclophosphamide often causes nausea, vomiting, and loss of appetite. However, it is very important that you continue to use the medicine even if you begin to feel ill. Do not stop taking this medicine without first checking with your doctor. Ask your doctor for ways to lessen these effects.
What are the long term side effects of cyclophosphamide?
The long-term side effects of cyclophosphamide (Cytoxan) are damage to the bladder and the bone marrow. Bladder cancer is a well-known risk and continues to arise at least 10-15 years after the drug was given.
What is the toxicity unique to cyclophosphamide?
Clinically, damage to the bladder (haemorrhagic cystitis), immunosuppression (when not desired) and alopecia are the most significant toxicities associated with cyclophosphamide. Cardiotoxicity is also a possibility when very high doses are given.
How do you manage the side effects of cyclophosphamide?
Nausea and vomiting can be severe. In some cases, drug therapy may be necessary to prevent or relieve nausea and vomiting. Changes in diet such as eating several small meals or limiting activity may help lessen some of these effects. If these effects persist or worsen, notify your doctor or pharmacist promptly.
What are the common side effects of carboplatin?
Stomach pain, body aches/pain, diarrhea, constipation, weakness, nausea, and vomiting may occur. Nausea and vomiting can be severe in some patients but usually go away within 24 hours of treatment. Drug therapy may be needed to prevent or relieve nausea and vomiting.
Is cyclophosphamide a strong chemotherapy?
Cyclophosphamide is one of a number of medications first developed as a chemotherapy drug (a medication used in the treatment of cancer). It was discovered that — in addition to its usefulness in cancer — cyclophosphamide also has a significant ability to suppress the immune system.
How bad is cyclophosphamide?
Cyclophosphamide, also called Cytoxan, is classified as a “cytotoxic agent”, because it has a toxic effect on many types of cells (“good” cells as well as “bad”). Cyclophosphamide is one of a number of medications first developed as a chemotherapy drug (a medication used in the treatment of cancer).
What is the antidote for cyclophosphamide?
No specific antidote for cyclophosphamide is known. Overdosage should be managed with supportive measures, including appropriate treatment for any concurrent infection, myelosuppression, or cardiac toxicity should it occur.
How is cyclophosphamide excreted?
Elimination. Cyclophosphamide is primarily excreted as metabolites. 10 to 20% is excreted unchanged in the urine and 4% is excreted in the bile following IV administration.
How is cyclophosphamide prevented?
2 mercaptoethane sulphone sodium (MESNA) prophylaxis is recommended espcially in patients receiving high dose cyclophosphamide. This drug combines with acrolein and detoxifies it, hence reducing the chances of baldder toxicity.
How much water should I drink with cyclophosphamide?
Follow your doctor’s instructions carefully about how much fluid to drink every day. Some patients may have to drink up to 7 to 12 cups (3 quarts) of fluid a day. Usually it is best to take cyclophosphamide first thing in the morning, to reduce the risk of bladder problems.
What are the side effects of taking Prempro?
Common side effects of Prempro include: stomach upset or pain. nausea. vomiting. bloating. breast tenderness/pain/swelling. headache.
What are the side effects of interferon therapy?
Early: Flu-like syndrome : Fever,chills,generalized aches and pains,headache,poor appetite.
What are the negative side effects of chemotherapy?
Nausea and vomiting. Chemotherapy can cause nausea (feeling sick to your stomach) and vomiting (throwing up). Whether you have these side effects, and how much, depends on the specific drugs and dose. The right medications given before and after each dose of chemotherapy can usually prevent nausea and vomiting.
